Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21870166 | 0.84 | KDM4E (0.73) | KDM4EMAPTSMN1; SMN2TSHRPOLB | |
| SCHEMBL29989633 | 0.79 | MAPT (1.00) | KDM4EMAPTSMN1; SMN2TSHRPOLB | |
| SCHEMBL4651272 | 0.79 | MAPT (1.00) | KDM4EMAPTSMN1; SMN2TSHRPOLB | |
| SCHEMBL26066041 | 0.78 | TP53 (0.63) | KDM4EMAPTSMN1; SMN2TSHRPOLB | |
| SCHEMBL17318564 | 0.78 | SMN1; SMN2 (0.57) | KDM4EMAPTSMN1; SMN2TSHRPOLB | |
| SCHEMBL20771350 | 0.78 | KDM4E (0.80) | KDM4EMAPTSMN1; SMN2TSHRPOLB | |
| SCHEMBL11196639 | 0.78 | SMN1; SMN2 (0.81) | KDM4EMAPTSMN1; SMN2TSHRPOLB | |
| SCHEMBL28637064 | 0.78 | MAPK1 (0.64) | KDM4EMAPTSMN1; SMN2TSHRPOLB | |
| SCHEMBL15886859 | 0.78 | MAPK1 (0.64) | KDM4EMAPTSMN1; SMN2TSHRPOLB | |
| SCHEMBL30061143 | 0.78 | MAPK1 (0.64) | KDM4EMAPTSMN1; SMN2TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3628374-B1 | BCL-3 INHIBITORS | UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2023-08-30 | — | — | EP | disclosed |