Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006148 | 0.89 | ADORA2A (0.41) | CCNCCDK8ADORA2AADORA1IDO1 | |
| SCHEMBL18006097 | 0.81 | HPGD (0.43) | IDO1MAPK14 | |
| SCHEMBL18006115 | 0.81 | CDK8 (0.41) | CCNCCDK8ADORA2AADORA1MAPK14 | |
| SCHEMBL1250229 | 0.81 | ERBB2 (0.47) | GRM5MYCLRRK2 | |
| SCHEMBL18006159 | 0.80 | ADORA1 (0.38) | ADORA2AADORA1GRM5 | |
| SCHEMBL18004342 | 0.79 | TAAR1 (0.44) | ADORA2AADORA1IDO1GRM5 | |
| SCHEMBL17969183 | 0.79 | ERBB2 (0.49) | GRM5MYCLRRK2 | |
| SCHEMBL18006160 | 0.78 | ADORA2A (0.39) | ADORA2AADORA1IDO1GRM5 | |
| SCHEMBL18005161 | 0.77 | MAPK14 (0.36) | ADORA2AADORA1IDO1MAPK14MAPK13 | |
| SCHEMBL18006010 | 0.77 | CCNC (0.40) | CCNCCDK8ADORA2AADORA1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |