SCHEMBL2607236

SCHEMBL2607236

CC(C)c1cccc(C(C)C)c1N1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(C)C5=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 4/20 0.55
DPP4 P27487 4/20 0.55
NR1H2 P55055 1/20 0.50
NR1H3 Q13133 1/20 0.50
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
USP2 O75604 3/20 0.43
KEAP1 Q14145 2/20 0.43
NFE2L2 Q16236 2/20 0.43
ATM Q13315 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
POLB P06746 1/20 0.41
PRMT1 Q99873 1/20 0.41
TERT O14746 2/20 0.39
STAT3 P40763 1/20 0.38
HIF1A Q16665 1/20 0.38
CASP3 P42574 1/20 0.37
LMNA P02545 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13478139 0.94 ANPEP (0.60) ANPEPDPP4NR1H2NR1H3MEN1
SCHEMBL3438530 0.94 ANPEP (0.60) ANPEPDPP4NR1H2NR1H3MEN1
SCHEMBL18071847 0.94 ANPEP (0.60) ANPEPDPP4NR1H2NR1H3MEN1
SCHEMBL29369271 0.94 ANPEP (0.60) ANPEPDPP4NR1H2NR1H3MEN1
SCHEMBL29461625 0.94 ANPEP (0.60) ANPEPDPP4NR1H2NR1H3MEN1
SCHEMBL17151424 0.90 ANPEP (0.56) ANPEPDPP4NR1H2NR1H3MEN1
SCHEMBL20547100 0.89 ANPEP (0.52) ANPEPDPP4NR1H2NR1H3MEN1
SCHEMBL2704512 0.89 ANPEP (0.55) ANPEPDPP4NR1H2NR1H3MEN1
SCHEMBL30954668 0.88 ANPEP (0.67) ANPEPDPP4NR1H2NR1H3ALDH1A1
SCHEMBL17531021 0.88 ANPEP (0.67) ANPEPDPP4NR1H2NR1H3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120091449-A1 ORGANIC ELECTROLUMINESCENT ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-19 US disclosed