SCHEMBL260727

SCHEMBL260727

NC(=O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 1.00
LMNA P02545 1/20 0.88
GAA P10253 1/20 0.88
CES1 P23141 2/20 0.68
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
TDP1 Q9NUW8 1/20 0.65
ALDH1A1 P00352 2/20 0.63
MAPK1 P28482 2/20 0.63
CYP3A4 P08684 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
CES2 O00748 1/20 0.59
SRD5A2 P31213 1/20 0.59
GSK3B P49841 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.55
PLAU P00749 1/20 0.53
POLB P06746 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL27950892 1.00 TSHR (1.00) TSHRLMNAGAACES1CA1
Hydrochloric Acid SCHEMBL11203029 0.98 TSHR (0.96) TSHRLMNAGAACES1CA1
Hydrochloric Acid SCHEMBL27509957 0.96 TSHR (0.92) TSHRLMNAGAACES1CA1
Methyl Alcohol SCHEMBL27858599 0.96 TSHR (0.92) TSHRLMNAGAACES1CA1
SCHEMBL5696165 0.94 TSHR (0.88) TSHRLMNAGAACES1CA1
Acetic Acid SCHEMBL28100034 0.92 TSHR (0.85) TSHRLMNAGAACES1CA1
SCHEMBL27554215 0.92 TSHR (0.85) TSHRLMNAGAACES1CA1
Nitromide SCHEMBL9225099 0.90 TSHR (0.81) TSHRLMNAGAACES1CA1
SCHEMBL7905543 0.90 TSHR (0.81) TSHRLMNAGAACES1CA1
SCHEMBL30009929 0.89 TSHR (0.79) TSHRLMNAGAACES1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1496 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12429483-B2 System and method for determining onset and disease progression RESPIRATION SCAN LTD (IL) 2025-09-30 US claimed
CN-119715515-A Intelligent water quality detection device based on image recognition technology 暨南大学 2025-03-28 CN claimed
CN-114560787-B Preparation method of dabigatran etexilate intermediate p-aminobenzonitrile 内蒙古京科医药科技有限公司 2025-02-25 CN claimed
CN-119371298-A Method for efficiently synthesizing indenone compound 南阳师范学院 2025-01-28 CN claimed
EP-4103567-B1 SPIROCYCLIC INHIBITORS OF HEPATITIS B VIRUS OSPEDALE SAN RAFFAELE SRL (IT) 2024-10-23 EP claimed
CN-118812386-A Synthesis method of DB70 山东鄄城南港化工有限公司 2024-10-22 CN claimed
EP-3833672-B1 TRICYCLIC INHIBITORS OF HEPATITIS B VIRUS OSPEDALE SAN RAFFAELE SRL (IT) 2024-09-18 EP claimed
CN-116237059-B Modified hydrotalcite-loaded platinum ruthenium catalyst and preparation method and application thereof 沈阳化工研究院有限公司 2024-06-28 CN claimed
CN-115322156-B Non-coplanar benzimidazole diamine and preparation method and application thereof 东华大学 2024-05-28 CN claimed
CN-117848995-A Method for monitoring enzymatic reaction of amide substances, on-line monitoring and automatic control equipment 北京衍微科技有限公司 2024-04-09 CN claimed
US-4853415-A 2-(substituted sulfamyl) derivatives of 4-nitrobenzamide as radiation sensitizers MERCK & CO., INC. (US) 1989-08-01 US claimed
EP-0271713-A2 Method for preparing aqueous solutions containing chromogenic materials SAVYON DIAGNOSTICS LTD. (IL) 1988-06-22 EP claimed
US-4751288-A COLORFASTNESS BASF AKTIENGESELLSCHAFT (DE) 1988-06-14 US claimed
EP-0270292-A2 Radiation sensitizers MERCK & CO. INC. (US) 1988-06-08 EP claimed
EP-0253548-A2 Method for the determination of occult blood and chemical compositions therefor SAVYON DIAGNOSTICS LTD. (IL) 1988-01-20 EP claimed
US-4604460-A ANTIBIOTICS, BACTERICIDES SHIONOGI & CO., LTD. (JP) 1986-08-05 US claimed
US-4443598-A ANTIBIOTICS AND INTERMEDIATES SHIONOGI & CO., LTD. (JP) 1984-04-17 US claimed
US-4260540-A SPIN DYEING POLYACRYLONITRILE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US claimed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US claimed
US-4014892-A ANTHELMINTICS AMERICAN CYANAMID COMPANY (US) 1977-03-29 US claimed