Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | BRAF | P15056 | 6/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26075760 | 0.92 | HDAC8 (0.54) | HDAC8HDAC6NR1H4KCNK3HDAC3 | |
| SCHEMBL22548671 | 0.91 | MEN1 (0.67) | KCNK3KCNK9RAB9AMEN1HTT | |
| SCHEMBL26075589 | 0.88 | BRAF (0.65) | BRAFCYP2C9 | |
| SCHEMBL26074245 | 0.88 | KCNK3 (0.66) | KCNK3KCNK9RAB9AMEN1KMT2A | |
| SCHEMBL26074365 | 0.85 | HDAC8 (0.62) | HDAC8HDAC6NR1H4KCNK3HDAC3 | |
| SCHEMBL15122844 | 0.85 | HDAC8 (0.66) | HDAC8HDAC6NR1H4KCNK3HDAC3 | |
| SCHEMBL17936114 | 0.82 | HDAC8 (0.58) | HDAC8HDAC6NR1H4KCNK3HDAC3 | |
| SCHEMBL20064059 | 0.82 | KCNK3 (0.77) | HDAC8HDAC6NR1H4KCNK3HDAC3 | |
| SCHEMBL16137326 | 0.81 | HDAC8 (0.70) | HDAC8HDAC6NR1H4KCNK3HDAC3 | |
| SCHEMBL20073121 | 0.81 | MAPT (0.67) | KCNK3KCNK9RAB9AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303570-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORP (US) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303570-A1 | KINASE INHIBITORS AND USES THEREOF | ERBB2, ERBB3, ERBB4 | HDAC8 3360/4885HDAC6 3545/4885NR1H4 2474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.