Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1I | Q9P0X4 | 15/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 14/20 | 0.52 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26082512 | 0.85 | CACNA1I (0.63) | CACNA1IKCNH2CACNA1HCACNA1GCYP2D6 | |
| SCHEMBL26081970 | 0.83 | CACNA1I (0.54) | CACNA1IKCNH2CACNA1HCACNA1GCYP2D6 | |
| SCHEMBL26081996 | 0.83 | CACNA1I (0.46) | CACNA1IKCNH2CACNA1HCACNA1GHTR7 | |
| SCHEMBL26082509 | 0.83 | CACNA1I (0.61) | CACNA1IKCNH2CACNA1HCACNA1GCYP2D6 | |
| SCHEMBL26082107 | 0.82 | CACNA1I (0.61) | CACNA1IKCNH2CACNA1HCACNA1GCYP2D6 | |
| SCHEMBL26083444 | 0.82 | CACNA1I (0.48) | CACNA1IKCNH2CACNA1HCACNA1GCYP2D6 | |
| SCHEMBL26082506 | 0.81 | CACNA1I (0.61) | CACNA1IKCNH2CACNA1HCACNA1GCYP2D6 | |
| SCHEMBL26082511 | 0.81 | CACNA1I (0.52) | CACNA1IKCNH2CACNA1HCACNA1GCYP2D6 | |
| SCHEMBL26082102 | 0.81 | CACNA1H (0.51) | CACNA1IKCNH2CACNA1HCACNA1GCYP2D6 | |
| SCHEMBL26082097 | 0.81 | CACNA1H (0.51) | CACNA1IKCNH2CACNA1HCACNA1GCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192687-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING AN AZASPIROHEPTANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |