⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460532 | 0.84 | — | — | |
| SCHEMBL26084000 | 0.81 | — | — | |
| SCHEMBL1356446 | 0.78 | — | — | |
| SCHEMBL23228252 | 0.73 | — | — | |
| SCHEMBL9531657 | 0.72 | DPP4 (0.31) | — | |
| SCHEMBL14891058 | 0.71 | — | — | |
| SCHEMBL28997742 | 0.71 | — | — | |
| SCHEMBL13241201 | 0.70 | MAPK1 (0.31) | — | |
| SCHEMBL4402697 | 0.70 | — | — | |
| SCHEMBL8655255 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780835-B2 | Pyrazolo[3,4-b]pyridine compounds as inhibitors of TAM and MET kinases | ARRAY BIOPHARMA INC. (US) | 2023-10-10 | — | — | US | disclosed |