Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.65 |
| ▸ | NQO2 | P16083 | 2/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.56 |
| ▸ | TUBB | P07437 | 4/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.56 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.56 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.56 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.56 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.56 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.56 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2612725 | 0.93 | CYP19A1 (0.73) | CYP19A1NQO2TUBB4ATUBBTUBA3C | |
| SCHEMBL3059433 | 0.93 | CYP19A1 (0.73) | CYP19A1NQO2TUBB4ATUBBTUBA3C | |
| SCHEMBL19583395 | 0.91 | CYP1A1 (0.65) | CYP19A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19583396 | 0.91 | CYP1A1 (0.65) | CYP19A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL15096134 | 0.89 | CYP19A1 (0.63) | CYP19A1NQO2TUBB4ATUBBTUBA3C | |
| SCHEMBL13904959 | 0.87 | CYP19A1 (0.65) | CYP19A1NQO2TUBB4ATUBBTUBA3C | |
| SCHEMBL3765052 | 0.83 | CYP19A1 (0.79) | CYP19A1NQO2CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL13018885 | 0.83 | CYP19A1 (0.79) | CYP19A1NQO2CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL19003409 | 0.83 | CYP19A1 (0.60) | CYP19A1NQO2TUBB4ATUBBTUBA3C | |
| SCHEMBL13137567 | 0.83 | CYP19A1 (0.60) | CYP19A1NQO2TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170176469-A1 | Molecular Probes for Detecting Lipids | CASE WESTERN UNIVERSITY | 2017-06-22 | — | — | US | disclosed |
| US-9555130-B2 | Compositions and methods for in vivo imaging of myelin in the peripheral nervous system | CASE WESTERN RESERVE UNIVERSITY (US) | 2017-01-31 | — | — | US | disclosed |
| US-20120093727-A1 | COMPOSITIONS AND METHODS FOR IN VIVO IMAGING OF MYELIN IN THE PERIPHERAL NERVOUS SYSTEM | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-04-19 | — | — | US | disclosed |
| US-20100221180-A1 | IN VIVO IMAGING OF MYELINATION | WANG YANMING | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100221180-A1 | IN VIVO IMAGING OF MYELINATION | MAG, PMP22, MYT1 | CYP19A1 4871/4885NQO2 2223/4885TUBB4A 12/4885 |
| US-20120093727-A1 | COMPOSITIONS AND METHODS FOR IN VIVO IMAGING OF MYELIN IN THE PERIPHERAL NERVOUS SYSTEM | PMP22, MAG, MYT1 | CYP19A1 4802/4885NQO2 1809/4885TUBB4A 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.