Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.37 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30407784 | 1.00 | EPHX2 (0.44) | EPHX2HTR2AHTR2CCRBNGSPT1 | |
| SCHEMBL26436259 | 0.89 | EPHX2 (0.37) | EPHX2HTR2AHTR2CCRBNGSPT1 | |
| SCHEMBL30407728 | 0.89 | EPHX2 (0.37) | EPHX2HTR2AHTR2CCRBNGSPT1 | |
| SCHEMBL26435665 | 0.88 | CRBN (0.48) | EPHX2CRBNGSPT1DDB1 | |
| SCHEMBL30407969 | 0.88 | CRBN (0.48) | EPHX2CRBNGSPT1DDB1 | |
| SCHEMBL26089671 | 0.88 | CRBN (0.48) | EPHX2CRBNGSPT1DDB1 | |
| SCHEMBL31115909 | 0.82 | DDB1 (0.36) | EPHX2CRBNDDB1 | |
| SCHEMBL26434916 | 0.80 | CRBN (0.55) | EPHX2CRBNGSPT1DDB1 | |
| SCHEMBL26086762 | 0.80 | CRBN (0.55) | EPHX2CRBNGSPT1DDB1 | |
| SCHEMBL30349540 | 0.78 | CRBN (0.46) | CRBNGSPT1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069708-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND USES THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |