Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.49 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.41 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | IKZF3 | Q9UKT9 | 4/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | IL1B | P01584 | 1/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685641 | 1.00 | CRBN (0.49) | CRBNCSNK1A1IKZF1DDB1GSPT1 | |
| SCHEMBL22685506 | 0.93 | CRBN (0.51) | CRBNCSNK1A1IKZF1DDB1GSPT1 | |
| SCHEMBL22685595 | 0.90 | CRBN (0.53) | CRBNCSNK1A1IKZF1DDB1GSPT1 | |
| SCHEMBL22685649 | 0.89 | CRBN (0.50) | CRBNCSNK1A1IKZF1DDB1HDAC3 | |
| SCHEMBL26090241 | 0.89 | CRBN (0.50) | CRBNCSNK1A1IKZF1DDB1HDAC3 | |
| SCHEMBL22685807 | 0.89 | CRBN (0.51) | CRBNCSNK1A1IKZF1DDB1GSPT1 | |
| SCHEMBL22685623 | 0.88 | CRBN (0.61) | CRBNCSNK1A1IKZF1DDB1GSPT1 | |
| SCHEMBL22685599 | 0.88 | CRBN (0.52) | CRBNCSNK1A1IKZF1DDB1GSPT1 | |
| SCHEMBL22685626 | 0.87 | CRBN (0.51) | CRBNCSNK1A1IKZF1DDB1GSPT1 | |
| SCHEMBL22685541 | 0.87 | CRBN (0.53) | CRBNCSNK1A1IKZF1DDB1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023070120-A1 | KETOAMIDES FOR TREATING MALIGNANCY | BIOTHERYX, INC. (US) | 2023-04-27 | — | — | WO | claimed |