Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26450492 | 0.81 | EPHX2 (0.35) | GAAALDH1A1ALOX12AGTR1HTT | |
| SCHEMBL26091036 | 0.80 | KDM4E (0.33) | GAAALDH1A1ALOX12AGTR1HTT | |
| SCHEMBL26091033 | 0.80 | KDM4E (0.33) | GAAALDH1A1ALOX12AGTR1HTT | |
| SCHEMBL26684757 | 0.75 | — | — | |
| SCHEMBL26684752 | 0.75 | — | — | |
| SCHEMBL18393709 | 0.72 | CYP2C19 (0.30) | — | |
| SCHEMBL31532518 | 0.70 | CYP2C19 (0.37) | — | |
| SCHEMBL17276039 | 0.66 | CYP2C19 (0.39) | GAAALDH1A1 | |
| SCHEMBL9993653 | 0.65 | CYP2C19 (0.32) | — | |
| SCHEMBL23826026 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023067515-A1 | THIADIAZOLYL COMPOUNDS AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2023-04-27 | — | — | WO | disclosed |