SCHEMBL26094591

SCHEMBL26094591

CC=CC(=O)OCCCCCCCCCCCCC[SiH2]C(F)F

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.41
ATM Q13315 1/20 0.41
TSHR P16473 2/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 1/20 0.38
APP P05067 6/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HPGD P15428 1/20 0.32
HTT P42858 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
PRKCA P17252 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26095399 1.00 HCAR2 (0.41) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26093493 1.00 HCAR2 (0.41) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26095636 1.00 HCAR2 (0.41) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26093455 1.00 HCAR2 (0.41) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26092836 1.00 HCAR2 (0.41) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26095445 1.00 HCAR2 (0.41) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26094923 1.00 HCAR2 (0.41) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26095442 1.00 HCAR2 (0.41) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26092798 1.00 HCAR2 (0.41) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26094646 1.00 HCAR2 (0.41) HCAR2ATMTSHRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4174076-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS Shin-Etsu Chemical Co., Ltd. (JP) 2023-05-03 EP disclosed