Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.71 |
| ▸ | RICTOR | Q6R327 | 15/20 | 0.71 |
| ▸ | RPTOR | Q8N122 | 15/20 | 0.71 |
| ▸ | MAPKAP1 | Q9BPZ7 | 15/20 | 0.71 |
| ▸ | MLST8 | Q9BVC4 | 15/20 | 0.71 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HCK | P08631 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22494330 | 0.83 | MTOR (1.00) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494333 | 0.83 | MTOR (1.00) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL26095712 | 0.83 | MTOR (0.52) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL26093528 | 0.80 | MTOR (0.75) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494269 | 0.74 | MTOR (1.00) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494417 | 0.74 | MTOR (1.00) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL26095408 | 0.69 | PDE8B (0.38) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494342 | 0.67 | MTOR (0.70) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494344 | 0.67 | MTOR (0.70) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494446 | 0.64 | MTOR (1.00) | MTORRICTORRPTORMAPKAP1MLST8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3727389-B1 | COMPOUNDS AS MTOR INHIBITORS | GALDERMA RES & DEV (FR) | 2023-05-03 | — | — | EP | claimed |
| EP-3727389-B1 | COMPOUNDS AS MTOR INHIBITORS | GALDERMA RES & DEV (FR) | 2023-05-03 | — | — | EP | disclosed |