Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.52 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.52 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26097490 | 1.00 | P2RX1 (0.56) | P2RX1HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL30100454 | 1.00 | P2RX1 (0.56) | P2RX1HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL23675460 | 0.92 | P2RX1 (0.60) | P2RX1HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL26098433 | 0.92 | P2RX1 (0.60) | P2RX1HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL30100413 | 0.91 | HPGD (0.68) | P2RX1HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL30100509 | 0.91 | HPGD (0.68) | P2RX1HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL26095797 | 0.91 | HPGD (0.68) | P2RX1HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL17329358 | 0.91 | HPGD (0.68) | P2RX1HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL15889798 | 0.91 | HPGD (0.68) | P2RX1HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL4012461 | 0.90 | PTGER4 (0.64) | HPGDALDH1A1LMNAKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230140290-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | THE BOARD OF REGENTS OF THE UNIV OF TEXAS SY (US) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230140290-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | EIF2AK2, SARS1, ACE | P2RX1 3088/4885HPGD 1066/4885ALDH1A1 770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.