Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | GSK3A | P49840 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031330 | 0.86 | PDE4B (0.56) | KMT2AALDH1A1LMNA | |
| SCHEMBL6407514 | 0.80 | MEN1 (0.64) | KMT2AALDH1A1GSK3AGSK3BL3MBTL1 | |
| SCHEMBL30830857 | 0.79 | KMT2A (0.71) | KMT2AALDH1A1LMNASIGMAR1HSP90AA1 | |
| SCHEMBL31622245 | 0.78 | KMT2A (0.54) | KMT2AALDH1A1LMNASIGMAR1L3MBTL1 | |
| SCHEMBL1542663 | 0.76 | HSP90AA1 (0.71) | KMT2AALDH1A1GSK3AGSK3BLMNA | |
| SCHEMBL5493303 | 0.76 | RARG (0.53) | KMT2AALDH1A1GSK3AGSK3BLMNA | |
| SCHEMBL10341825 | 0.75 | KMT2A (0.57) | KMT2AALDH1A1LMNASIGMAR1HSP90AA1 | |
| SCHEMBL2191407 | 0.75 | KMT2A (0.56) | KMT2AALDH1A1LMNASIGMAR1L3MBTL1 | |
| SCHEMBL8320050 | 0.74 | SMN1; SMN2 (0.73) | KMT2AALDH1A1GSK3AGSK3BHTR1D | |
| SCHEMBL2559982 | 0.74 | RXFP1 (0.62) | KMT2AALDH1A1GSK3AGSK3BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136702-A1 | Inhibitors of Human Herpesviruses | THE GOVERNORS OF THE UNIVERSTIY OF ALBERTA (CA) | 2023-05-04 | — | — | US | disclosed |
| US-20230136702-A1 | Inhibitors of Human Herpesviruses | THE GOVERNORS OF THE UNIVERSTIY OF ALBERTA (CA) | 2023-05-04 | — | — | US | disclosed |
| US-20230136702-A1 | Inhibitors of Human Herpesviruses | THE GOVERNORS OF THE UNIVERSTIY OF ALBERTA (CA) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136702-A1 | Inhibitors of Human Herpesviruses | RPL5, RPL35, HAVCR2 | KMT2A 329/4885ALDH1A1 1582/4885GSK3A 846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.