Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 7/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 8/20 | 0.46 |
| ▸ | CSF1R | P07333 | 4/20 | 0.46 |
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 9/20 | 0.46 |
| ▸ | FLT3 | P36888 | 6/20 | 0.46 |
| ▸ | BRAF | P15056 | 2/20 | 0.44 |
| ▸ | FLT1 | P17948 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30393114 | 1.00 | EGFR (0.50) | EGFRERBB2KDRPDGFRBCSF1R | |
| SCHEMBL26536031 | 0.92 | EGFR (0.52) | EGFRERBB2KDRPDGFRBCSF1R | |
| SCHEMBL30394681 | 0.92 | EGFR (0.52) | EGFRERBB2KDRPDGFRBCSF1R | |
| SCHEMBL30393989 | 0.90 | EGFR (0.50) | EGFRERBB2KDRPDGFRBCSF1R | |
| SCHEMBL26102970 | 0.90 | EGFR (0.50) | EGFRERBB2KDRPDGFRBCSF1R | |
| SCHEMBL26100120 | 0.89 | EGFR (0.55) | EGFRERBB2KDRPDGFRBCSF1R | |
| SCHEMBL26136013 | 0.88 | EGFR (0.53) | EGFRERBB2KDRPDGFRBKIT | |
| SCHEMBL30394387 | 0.88 | EGFR (0.53) | EGFRERBB2KDRPDGFRBKIT | |
| SCHEMBL30393135 | 0.87 | EGFR (0.48) | EGFRERBB2KDRPDGFRBCSF1R | |
| SCHEMBL26132918 | 0.87 | EGFR (0.48) | EGFRERBB2KDRPDGFRBCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | claimed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |