Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.61 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.61 |
| ▸ | STAT3 | P40763 | 5/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.37 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26099776 | 1.00 | CRBN (0.61) | CRBNDDB1STAT3TRIM24GSPT1 | |
| SCHEMBL30289415 | 0.99 | CRBN (0.62) | CRBNDDB1STAT3TRIM24GSPT1 | |
| SCHEMBL20840207 | 0.96 | CRBN (0.60) | CRBNDDB1STAT3TRIM24GSPT1 | |
| SCHEMBL20840317 | 0.96 | CRBN (0.60) | CRBNDDB1STAT3TRIM24GSPT1 | |
| SCHEMBL20840314 | 0.96 | CRBN (0.60) | CRBNDDB1STAT3TRIM24GSPT1 | |
| SCHEMBL20840210 | 0.96 | CRBN (0.60) | CRBNDDB1STAT3TRIM24GSPT1 | |
| SCHEMBL31710038 | 0.91 | DDB1 (0.65) | CRBNDDB1STAT3GSPT1 | |
| SCHEMBL26635043 | 0.90 | CRBN (0.68) | CRBNDDB1GSPT1 | |
| SCHEMBL30392669 | 0.89 | DDB1 (0.65) | CRBNDDB1STAT3 | |
| SCHEMBL26099555 | 0.89 | DDB1 (0.65) | CRBNDDB1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076161-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |