Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26099842 | 0.91 | CRBN (0.47) | CRBNDDB1CMA1 | |
| SCHEMBL26096014 | 0.89 | CRBN (0.48) | CRBNDDB1CMA1 | |
| SCHEMBL26096056 | 0.88 | CRBN (0.48) | CRBNDDB1CMA1 | |
| SCHEMBL26101689 | 0.85 | CRBN (0.45) | CRBNDDB1CMA1 | |
| SCHEMBL26101788 | 0.85 | CRBN (0.42) | CRBNDDB1 | |
| SCHEMBL26092987 | 0.84 | CRBN (0.50) | CRBNDDB1CMA1 | |
| Trifluoroacetic Acid SCHEMBL30392459 | 0.79 | DDB1 (0.44) | CRBNDDB1CMA1 | |
| Trifluoroacetic Acid SCHEMBL26101539 | 0.78 | CRBN (0.51) | CRBNDDB1CMA1 | |
| SCHEMBL26506352 | 0.78 | CRBN (0.60) | CRBNDDB1 | |
| SCHEMBL26100060 | 0.77 | CRBN (0.58) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076161-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |