Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 8/20 | 0.50 |
| ▸ | KDR | P35968 | 4/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 3/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26099433 | 0.92 | EGFR (0.52) | EGFRPDGFRBKDRKITFLT3 | |
| SCHEMBL30394281 | 0.92 | EGFR (0.52) | EGFRPDGFRBKDRKITFLT3 | |
| SCHEMBL26103039 | 0.90 | EGFR (0.50) | EGFRPDGFRBKDRKITFLT3 | |
| SCHEMBL26102918 | 0.85 | EGFR (0.51) | EGFRKDRROCK2KIT | |
| SCHEMBL26100883 | 0.85 | KIT (0.51) | EGFRPDGFRBKDRKITFLT3 | |
| SCHEMBL30394096 | 0.85 | EGFR (0.51) | EGFRKDRROCK2KIT | |
| SCHEMBL26102438 | 0.84 | AURKA (0.49) | EGFRPDGFRBKDRKIT | |
| SCHEMBL29238247 | 0.84 | KIT (0.50) | EGFRPDGFRBKDRROCK2KIT | |
| SCHEMBL30393851 | 0.84 | AURKA (0.49) | EGFRPDGFRBKDRKIT | |
| SCHEMBL26102091 | 0.84 | PDGFRB (0.48) | EGFRPDGFRBKDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |