SCHEMBL26099642 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	KIT	P10721	10/20	0.68

▸	EGFR	P00533	10/20	0.56

▸	KDR	P35968	9/20	0.56

▸	AURKA	O14965	3/20	0.54

▸	ERBB2	P04626	3/20	0.54

▸	TEK	Q02763	3/20	0.54

▸	AURKB	Q96GD4	3/20	0.54

▸	PDGFRB	P09619	2/20	0.54

▸	FLT4	P35916	2/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30394566	0.88	EGFR (0.57)	KITEGFRKDRAURKAERBB2
SCHEMBL26103102	0.88	EGFR (0.57)	KITEGFRKDRAURKAERBB2
SCHEMBL26102545	0.86	EGFR (0.53)	KITEGFRKDRAURKAERBB2
SCHEMBL26136777	0.84	AURKA (0.57)	KITEGFRKDRAURKAERBB2
SCHEMBL31137787	0.84	AURKA (0.57)	KITEGFRKDRAURKAERBB2
SCHEMBL26101516	0.84	KDR (0.63)	EGFRKDRAURKAERBB2TEK
SCHEMBL30891810	0.84	KDR (0.55)	KITEGFRKDRAURKAERBB2
SCHEMBL26101967	0.84	KDR (0.55)	KITEGFRKDRAURKAERBB2
SCHEMBL26099640	0.84	KIT (0.52)	KITEGFRKDRAURKAERBB2
Hydrochloric Acid SCHEMBL30394719	0.83	KDR (0.56)	KITEGFRKDRAURKAERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023075529-A1	QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF	보로노이바이오 주식회사	2023-05-04	—	—	WO	claimed