Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 4/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | KIT | P10721 | 2/20 | 0.44 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 4/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30393123 | 1.00 | EPHA2 (0.47) | EPHA2ERBB2EPHB4EGFRKIT | |
| SCHEMBL26534201 | 1.00 | EPHA2 (0.47) | EPHA2ERBB2EPHB4EGFRKIT | |
| SCHEMBL26103424 | 1.00 | EPHA2 (0.47) | EPHA2ERBB2EPHB4EGFRKIT | |
| SCHEMBL30394779 | 1.00 | EPHA2 (0.47) | EPHA2ERBB2EPHB4EGFRKIT | |
| SCHEMBL30394645 | 0.97 | EPHA2 (0.45) | EPHA2ERBB2EPHB4EGFRKIT | |
| SCHEMBL26136499 | 0.97 | EPHA2 (0.45) | EPHA2ERBB2EPHB4EGFRKIT | |
| SCHEMBL26136507 | 0.96 | EPHA2 (0.47) | EPHA2ERBB2EPHB4EGFRKIT | |
| SCHEMBL30394773 | 0.96 | EPHA2 (0.47) | EPHA2ERBB2EPHB4EGFRKIT | |
| SCHEMBL26535755 | 0.96 | EPHA2 (0.47) | EPHA2ERBB2EPHB4EGFRKIT | |
| SCHEMBL26101664 | 0.92 | KIT (0.48) | ERBB2EGFRKITMAPK7KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | claimed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |