Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.48 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30392650 | 1.00 | TYK2 (0.48) | TYK2GPR52PDE4D | |
| SCHEMBL26100155 | 0.85 | TYK2 (0.46) | TYK2PDE4D | |
| SCHEMBL31162001 | 0.83 | TYK2 (0.46) | TYK2GPR52PDE4D | |
| SCHEMBL26099988 | 0.83 | TYK2 (0.46) | TYK2GPR52PDE4D | |
| SCHEMBL26101546 | 0.82 | TYK2 (0.49) | TYK2PDE4D | |
| Trifluoroacetic Acid SCHEMBL31161866 | 0.82 | TYK2 (0.44) | TYK2PDE4D | |
| SCHEMBL26102578 | 0.82 | TYK2 (0.45) | TYK2PDE4D | |
| SCHEMBL31161630 | 0.81 | TYK2 (0.48) | TYK2GPR52PDE4D | |
| SCHEMBL26102661 | 0.81 | TYK2 (0.48) | TYK2PDE4D | |
| Trifluoroacetic Acid SCHEMBL31161475 | 0.81 | TYK2 (0.43) | TYK2GPR52PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076161-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |