Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 4/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101669 | 0.96 | KIT (0.48) | KITEGFRMAPK7KDRSLC2A1 | |
| SCHEMBL26102390 | 0.96 | KIT (0.48) | KITEGFRMAPK7KDRSLC2A1 | |
| SCHEMBL26101664 | 0.96 | KIT (0.48) | KITEGFRMAPK7KDRSLC2A1 | |
| SCHEMBL26535311 | 0.94 | KIT (0.47) | KITEGFRMAPK7KDRSLC2A1 | |
| SCHEMBL29238264 | 0.93 | KDR (0.53) | KITEGFRKDR | |
| SCHEMBL30394389 | 0.93 | KDR (0.53) | KITEGFRKDR | |
| SCHEMBL26100466 | 0.92 | KIT (0.47) | KITEGFRMAPK7KDRSLC2A1 | |
| SCHEMBL26102923 | 0.92 | KIT (0.47) | KITEGFRMAPK7KDRSLC2A1 | |
| SCHEMBL30394645 | 0.92 | EPHA2 (0.45) | KITEGFRMAPK7KDRSLC2A1 | |
| SCHEMBL26136499 | 0.92 | EPHA2 (0.45) | KITEGFRMAPK7KDRSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |