Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.54 |
| ▸ | EGFR | P00533 | 15/20 | 0.54 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 7/20 | 0.51 |
| ▸ | TEK | Q02763 | 7/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.51 |
| ▸ | FLT4 | P35916 | 5/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.51 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.51 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | KIF5B | P33176 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101506 | 0.91 | KDR (0.53) | KDREGFRKITAURKATEK | |
| SCHEMBL26103279 | 0.88 | EGFR (0.53) | KDREGFRKITAURKATEK | |
| SCHEMBL26101510 | 0.87 | KDR (0.53) | KDREGFRKITAURKATEK | |
| SCHEMBL30891764 | 0.86 | KDR (0.59) | KDREGFRKITAURKATEK | |
| SCHEMBL26099266 | 0.86 | KDR (0.59) | KDREGFRKITAURKATEK | |
| SCHEMBL26101653 | 0.86 | KDR (0.51) | KDREGFRKITAURKATEK | |
| SCHEMBL30891810 | 0.86 | KDR (0.55) | KDREGFRKITAURKATEK | |
| SCHEMBL26101967 | 0.86 | KDR (0.55) | KDREGFRKITAURKATEK | |
| SCHEMBL26099640 | 0.86 | KIT (0.52) | KDREGFRKITAURKATEK | |
| Hydrochloric Acid SCHEMBL30394719 | 0.85 | KDR (0.56) | KDREGFRKITAURKATEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |