Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 5/20 | 0.45 |
| ▸ | KDR | P35968 | 6/20 | 0.44 |
| ▸ | FLT4 | P35916 | 5/20 | 0.44 |
| ▸ | EGFR | P00533 | 5/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.44 |
| ▸ | FLT1 | P17948 | 4/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | BRAF | P15056 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30394834 | 1.00 | KIT (0.45) | KITKDRFLT4EGFRFGFR1 | |
| SCHEMBL26536043 | 0.97 | KDR (0.46) | KITKDRFLT4EGFRFGFR1 | |
| SCHEMBL30891790 | 0.97 | KDR (0.46) | KITKDRFLT4EGFRFGFR1 | |
| SCHEMBL26102350 | 0.97 | KDR (0.46) | KITKDRFLT4EGFRFGFR1 | |
| SCHEMBL30891758 | 0.93 | KIT (0.47) | KITKDRFLT4EGFRFGFR1 | |
| SCHEMBL26101744 | 0.93 | KIT (0.47) | KITKDRFLT4EGFRFGFR1 | |
| SCHEMBL26099914 | 0.93 | KIT (0.47) | KITKDRFLT4EGFRFGFR1 | |
| SCHEMBL26099909 | 0.93 | KIT (0.47) | KITKDRFLT4EGFRFGFR1 | |
| SCHEMBL30891793 | 0.93 | KIT (0.47) | KITKDRFLT4EGFRFGFR1 | |
| SCHEMBL30394313 | 0.90 | AURKA (0.48) | KITKDRFLT4EGFRFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |