SCHEMBL26104399

SCHEMBL26104399

CC1CCCN(Cc2cc(C3CC3)c3occ(-c4cccc(C5(c6nncn6C)CC(C)C5)c4)c(=O)c3c2)C1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CBLB Q13191 20/20 0.60
CBL P22681 16/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26104394 1.00 CBLB (0.60) CBLBCBL
SCHEMBL30311422 1.00 CBLB (0.60) CBLBCBL
SCHEMBL29254105 0.92 CBLB (0.71) CBLBCBL
SCHEMBL26481390 0.92 CBLB (0.71) CBLBCBL
SCHEMBL30938782 0.92 CBLB (0.71) CBLBCBL
SCHEMBL30311392 0.91 CBLB (0.48) CBLBCBL
SCHEMBL26106793 0.91 CBLB (0.48) CBLBCBL
SCHEMBL26106801 0.91 CBLB (0.48) CBLBCBL
SCHEMBL26481499 0.90 CBLB (0.58) CBLBCBL
SCHEMBL26481226 0.90 CBLB (0.64) CBLBCBL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118139856-A Parallel-ring compounds as Cbl-b inhibitors 海南先声再明医药股份有限公司 2024-06-04 CN disclosed
WO-2023072273-A1 POLYCYCLIC COMPOUND AS CBL-B INHIBITOR 先声再明医药有限公司 2023-05-04 WO disclosed