Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.70 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3042514 | 0.88 | ADORA2A (0.70) | ADORA2ANUDT1CYP1A2ALDH1A1HPGD | |
| SCHEMBL27310325 | 0.83 | ADORA2A (1.00) | ADORA2ANUDT1CYP1A2ALDH1A1HPGD | |
| SCHEMBL3035401 | 0.79 | ADORA2A (0.56) | ADORA2ANUDT1CYP1A2ALDH1A1HPGD | |
| SCHEMBL3040419 | 0.79 | ADORA2A (0.70) | ADORA2ANUDT1CYP1A2ALDH1A1HPGD | |
| SCHEMBL3029368 | 0.74 | ADORA2A (0.79) | ADORA2ANUDT1DCPS | |
| SCHEMBL17959853 | 0.72 | ADORA2A (0.69) | ADORA2ANUDT1DHODH | |
| SCHEMBL12743677 | 0.72 | CSNK2A2 (0.69) | ADORA2ACYP1A2ALDH1A1HSD17B10DHODH | |
| SCHEMBL27400918 | 0.71 | ADORA2A (0.71) | ADORA2ANUDT1CYP1A2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL10584167 | 0.70 | ADORA2A (0.69) | ADORA2ANUDT1CYP1A2ALDH1A1HPGD | |
| SCHEMBL421987 | 0.70 | ADORA2A (1.00) | ADORA2ANUDT1CYP1A2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072026-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-05-04 | — | — | WO | disclosed |