Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30310137 | 0.81 | CYP19A1 (0.45) | CYP19A1CYP3A4HSP90AA1KDM4EP2RX7 | |
| SCHEMBL26102426 | 0.81 | CYP19A1 (0.45) | CYP19A1CYP3A4HSP90AA1KDM4EP2RX7 | |
| SCHEMBL11970656 | 0.81 | CYP19A1 (0.45) | CYP19A1CYP3A4HSP90AA1KDM4EP2RX7 | |
| SCHEMBL16091462 | 0.78 | CYP19A1 (0.52) | CYP19A1CYP3A4HSP90AA1KDM4EP2RX7 | |
| SCHEMBL11970541 | 0.77 | CYP19A1 (0.41) | CYP19A1CYP3A4HSP90AA1 | |
| SCHEMBL5669602 | 0.75 | CYP19A1 (0.49) | CYP19A1CYP3A4HSP90AA1KDM4EP2RX7 | |
| SCHEMBL27886405 | 0.74 | CYP19A1 (0.47) | CYP19A1CYP3A4HSP90AA1KDM4EP2RX7 | |
| SCHEMBL14677129 | 0.74 | CYP19A1 (0.39) | CYP19A1CYP3A4 | |
| SCHEMBL4266127 | 0.73 | CYP19A1 (0.55) | CYP19A1CYP3A4HSP90AA1P2RX7 | |
| SCHEMBL179269 | 0.73 | CYP19A1 (0.46) | CYP19A1CYP3A4HSP90AA1KDM4EP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118139854-A | Modulators of CCR6 receptors | 爱杜西亚药品有限公司 | 2024-06-04 | — | — | CN | claimed |
| WO-2023073082-A1 | CCR6 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-05-04 | — | — | WO | claimed |
| CN-118139854-A | Modulators of CCR6 receptors | 爱杜西亚药品有限公司 | 2024-06-04 | — | — | CN | disclosed |
| WO-2023073082-A1 | CCR6 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-05-04 | — | — | WO | disclosed |