Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30591764 | 1.00 | TRPV1 (0.41) | TRPV1TRPA1SCN9ASCN10APDE10A | |
| SCHEMBL26104463 | 0.87 | TRPV1 (0.41) | TRPV1TRPA1SCN9ASCN10APDE10A | |
| SCHEMBL30591660 | 0.87 | TRPV1 (0.41) | TRPV1TRPA1SCN9ASCN10APDE10A | |
| SCHEMBL26106899 | 0.86 | TRPV1 (0.39) | TRPV1TRPA1PDE10AALDH1A1 | |
| SCHEMBL30591749 | 0.86 | TRPV1 (0.39) | TRPV1TRPA1PDE10AALDH1A1 | |
| SCHEMBL30591823 | 0.82 | SCN9A (0.42) | SCN9ASCN10APDE10A | |
| SCHEMBL26108593 | 0.82 | SCN9A (0.42) | SCN9ASCN10APDE10A | |
| SCHEMBL26105333 | 0.79 | PDE10A (0.37) | SCN9ASCN10APDE10A | |
| SCHEMBL30591723 | 0.79 | PDE10A (0.42) | SCN9APDE10A | |
| SCHEMBL30591932 | 0.78 | EPHX2 (0.47) | SCN9ASCN10APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | claimed |
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |