Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 6/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | ABL2 | P42684 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30582566 | 1.00 | KIT (0.46) | KITSRCEGFRABL1ABL2 | |
| SCHEMBL30582562 | 0.88 | SRC (0.40) | KITSRCEGFRABL1ABL2 | |
| SCHEMBL26109440 | 0.88 | SRC (0.40) | KITSRCEGFRABL1ABL2 | |
| SCHEMBL26106956 | 0.87 | HDAC2 (0.39) | KITSRCEGFRABL1ABL2 | |
| SCHEMBL30582607 | 0.87 | HDAC2 (0.39) | KITSRCEGFRABL1ABL2 | |
| SCHEMBL26107804 | 0.87 | SRC (0.42) | KITSRCEGFRABL1ABL2 | |
| SCHEMBL30582630 | 0.87 | SRC (0.42) | KITSRCEGFRABL1ABL2 | |
| SCHEMBL30582604 | 0.87 | SRC (0.40) | SRCEGFRABL1ABL2RET | |
| SCHEMBL30582636 | 0.87 | HDAC2 (0.44) | SRCEGFRABL1ABL2RET | |
| SCHEMBL26134541 | 0.87 | SRC (0.40) | SRCEGFRABL1ABL2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024091370-A1 | 5,6-FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |