Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 15/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30591853 | 1.00 | TRPV1 (0.43) | TRPV1MAPTCA12CA1CA2 | |
| SCHEMBL26106106 | 0.89 | JAK2 (0.42) | TRPV1 | |
| SCHEMBL30591650 | 0.89 | JAK2 (0.42) | TRPV1 | |
| SCHEMBL26106865 | 0.89 | JAK2 (0.42) | TRPV1 | |
| SCHEMBL30591860 | 0.89 | JAK2 (0.42) | TRPV1 | |
| SCHEMBL31474524 | 0.87 | TRPV1 (0.53) | TRPV1MAPT | |
| SCHEMBL26105173 | 0.83 | TRPV1 (0.44) | TRPV1CA12CA1CA2CA9 | |
| SCHEMBL30591912 | 0.83 | TRPV1 (0.44) | TRPV1CA12CA1CA2CA9 | |
| SCHEMBL30591794 | 0.82 | TRPV1 (0.45) | TRPV1CA12CA1CA2CA9 | |
| SCHEMBL26108054 | 0.82 | TRPV1 (0.45) | TRPV1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | claimed |