Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 13/20 | 0.42 |
| ▸ | BTK | Q06187 | 4/20 | 0.42 |
| ▸ | ITK | Q08881 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30591759 | 1.00 | EGFR (0.42) | EGFRBTKITKTRPV1KRAS | |
| SCHEMBL26108742 | 0.87 | TRPV1 (0.50) | TRPV1KIT | |
| SCHEMBL30591801 | 0.87 | TRPV1 (0.50) | TRPV1KIT | |
| SCHEMBL30591708 | 0.86 | EGFR (0.42) | EGFRBTKITK | |
| SCHEMBL26108008 | 0.86 | EGFR (0.42) | EGFRBTKITK | |
| SCHEMBL26107144 | 0.82 | EGFR (0.43) | EGFRBTKTRPV1KIT | |
| SCHEMBL30591862 | 0.82 | EGFR (0.43) | EGFRBTKTRPV1KIT | |
| SCHEMBL30591849 | 0.81 | TRPV1 (0.39) | EGFRBTKTRPV1KRAS | |
| SCHEMBL30591667 | 0.81 | TRPV1 (0.53) | EGFRTRPV1KIT | |
| SCHEMBL26108175 | 0.81 | TRPV1 (0.53) | EGFRTRPV1KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |