Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | BTK | Q06187 | 3/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26108662 | 0.99 | FLT3 (0.34) | FLT3HRH3ITKKCNH2BTK | |
| SCHEMBL26108721 | 0.97 | KCNH2 (0.33) | FLT3HRH3ITKKCNH2BTK | |
| SCHEMBL26111158 | 0.92 | — | — | |
| SCHEMBL26107996 | 0.91 | ITK (0.35) | ITKBTKRET | |
| SCHEMBL26109498 | 0.88 | FGFR1 (0.31) | — | |
| SCHEMBL26109846 | 0.88 | KCNH2 (0.36) | FLT3ITKKCNH2BTKRET | |
| SCHEMBL30582525 | 0.86 | ITK (0.44) | FLT3ITKBTK | |
| SCHEMBL26106008 | 0.85 | ITK (0.35) | ITKRET | |
| SCHEMBL30582513 | 0.85 | ITK (0.44) | FLT3ITKBTK | |
| SCHEMBL26108434 | 0.84 | KCNH2 (0.30) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | claimed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |