Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26110636 | 1.00 | TSHR (0.45) | TSHRMAPTGAASMN1; SMN2ATM | |
| SCHEMBL26683413 | 1.00 | TSHR (0.45) | TSHRMAPTGAASMN1; SMN2ATM | |
| SCHEMBL26648985 | 1.00 | TSHR (0.45) | TSHRMAPTGAASMN1; SMN2ATM | |
| SCHEMBL11592910 | 0.91 | TSHR (0.52) | TSHRMAPTGAASMN1; SMN2ATM | |
| SCHEMBL29942704 | 0.88 | TSHR (0.54) | TSHRMAPTGAASMN1; SMN2ATM | |
| SCHEMBL29942458 | 0.88 | TSHR (0.54) | TSHRMAPTGAASMN1; SMN2ATM | |
| SCHEMBL11069033 | 0.88 | — | — | |
| SCHEMBL20820011 | 0.85 | — | — | |
| SCHEMBL20820009 | 0.85 | — | — | |
| SCHEMBL21050630 | 0.80 | TSHR (0.43) | TSHRMAPTGAASMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196283-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2023-10-12 | — | — | WO | disclosed |