Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.39 |
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.39 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30632531 | 1.00 | KDM1A (0.51) | KDM1ABCHENAMPTNOTUMMAPK1 | |
| SCHEMBL16385108 | 0.84 | NOTUM (0.47) | KDM1ABCHENAMPTNOTUMMAPK1 | |
| SCHEMBL16353535 | 0.84 | NOTUM (0.47) | KDM1ABCHENAMPTNOTUMMAPK1 | |
| SCHEMBL16353667 | 0.84 | NOTUM (0.47) | KDM1ABCHENAMPTNOTUMMAPK1 | |
| SCHEMBL14587287 | 0.84 | KDM1A (0.46) | KDM1ABCHENAMPTNOTUMMAPK1 | |
| SCHEMBL14587286 | 0.84 | KDM1A (0.46) | KDM1ABCHENAMPTNOTUMMAPK1 | |
| SCHEMBL6648174 | 0.84 | NOTUM (0.47) | KDM1ABCHENAMPTNOTUMMAPK1 | |
| SCHEMBL7633049 | 0.82 | MCL1 (0.46) | KDM1ABCHENAMPTNOTUMMAPK1 | |
| SCHEMBL12376485 | 0.81 | KDM1A (0.44) | KDM1ABCHENAMPTNOTUMMAPK1 | |
| SCHEMBL8567308 | 0.81 | NAMPT (0.46) | KDM1ABCHENAMPTNOTUMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192375-A1 | HSD17B13 INHIBITORS AND USES THEREOF | FL2022-001, INC. (US) | 2023-10-05 | — | — | WO | disclosed |