Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1164489 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL5118035 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL14609981 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL26113894 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL204928 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL5122115 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL25417193 | 0.79 | HTT (0.42) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL26114198 | 0.78 | POLB (0.38) | SMN1; SMN2RAB9AGAAMAPK1KMT2A | |
| SCHEMBL5127061 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL14012890 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023180472-A1 | HYDROXYMETHYL AZABICYCLO[2.2.1]HEPTANES AND MEDICAL USES THEREOF | ATROGI AB (SE) | 2023-09-28 | — | — | WO | disclosed |