⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691196 | 1.00 | — | — | |
| SCHEMBL894031 | 1.00 | — | — | |
| SCHEMBL21436820 | 0.73 | — | — | |
| SCHEMBL142518 | 0.72 | — | — | |
| SCHEMBL231002 | 0.72 | — | — | |
| SCHEMBL28690676 | 0.71 | — | — | |
| SCHEMBL22254242 | 0.69 | — | — | |
| SCHEMBL14080957 | 0.69 | — | — | |
| SCHEMBL515123 | 0.69 | — | — | |
| SCHEMBL1233578 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 986 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4380932-B1 | PROCESS FOR PREPARING AFICAMTEN | CYTOKINETICS INC (US) | 2025-11-26 | — | — | EP | claimed |
| EP-4055015-B1 | GEM-DISUBSTITUTED HETEROCYCLIC COMPOUNDS AND THEIR USE AS IDH INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2025-04-02 | — | — | EP | claimed |
| US-12247024-B2 | Process for preparing aficamten | CYTOKINETICS, INC. (US) | 2025-03-11 | — | — | US | claimed |
| US-12227522-B2 | Synthesis of structural analogs of largazole and associated compounds | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2025-02-18 | — | — | US | claimed |
| EP-4380932-A1 | PROCESS FOR PREPARING AFICAMTEN | Cytokinetics, Inc. (US) | 2024-06-12 | — | — | EP | claimed |
| US-20240150336-A1 | PROCESS FOR PREPARING AFICAMTEN | CYTOKINETICS, INC. | 2024-05-09 | — | — | US | claimed |
| US-11932631-B2 | Process for preparing aficamten | CYTOKINETICS, INC. (US) | 2024-03-19 | — | — | US | claimed |
| US-20240059709-A1 | SYNTHESIS OF STRUCTURAL ANALOGS OF LARGAZOLE AND ASSOCIATED COMPOUNDS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2024-02-22 | — | — | US | claimed |
| EP-4262795-A1 | SYNTHESIS OF STRUCTURAL ANALOGS OF LARGAZOLE AND ASSOCIATED COMPOUNDS | Colorado State University Research Foundation (US) | 2023-10-25 | — | — | EP | claimed |
| EP-3768659-B1 | AN IMPROVED ASYMMETRIC SYNTHESIS OF ALPHA-(DIARYLMETHYL) ALKYL AMINES | PIRAMAL PHARMA LTD (IN) | 2023-07-19 | — | — | EP | claimed |
| US-20210061752-A1 | AN IMPROVED ASYMMETRIC SYNTHESIS OF alpha-(DIARYLMETHYL) ALKYL AMINES | Piramal Enterprises Limited (IN) | 2021-03-04 | — | — | US | claimed |
| US-10858315-B2 | Method for preparing (R)-N-[4-(1-amino-ethyl)-2,6-difluoro-phenyl]-methanesulfonamide | AMOREPACIFIC CORPORATION (KR) | 2020-12-08 | — | — | US | claimed |
| US-20200031766-A1 | METHOD FOR PREPARING (R)-N-[4-(1-AMINO-ETHYL)-2,6-DIFLUORO-PHENYL]-METHANESULFONAMIDE | AMOREPACIFIC CORPORATION (KR) | 2020-01-30 | — | — | US | claimed |
| US-20190144454-A1 | COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO KIT | BLUEPRINT MEDICINES CORPORATION | 2019-05-16 | — | — | US | claimed |
| EP-3409674-A1 | COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO KIT | Blueprint Medicines Corporation (US) | 2018-12-05 | — | — | EP | claimed |
| US-20140256952-A1 | PROCESS FOR IXABEPILONE, AND INTERMEDIATES THEREOF | SCINOPHARM TAIWAN, LTD. (TW) | 2014-09-11 | — | — | US | claimed |
| US-20070254929-A1 | Fluoro-and trifluoroalkyl-containing heterocyclic sulfonamide inhibitors of beta amyloid production and derivatives thereof | WYETH (US) | 2007-11-01 | — | — | US | claimed |
| EP-1608638-A1 | FLUORO-AND TRIFLUOROALKYL-CONTAINING HETEROCYCLIC SULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION AND DERIVATIVES THEREOF | Wyeth (US) | 2005-12-28 | — | — | EP | claimed |
| WO-2004092155-A1 | FLUORO-AND TRIFLUOROALKYL-CONTAINING HETEROCYCLIC SULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION AND DERIVATIVES THEREOF | WYETH (US) | 2004-10-28 | — | — | WO | claimed |
| US-20040198778-A1 | Fluoro- and trifluoroalkyl-containing heterocyclic sulfonamide inhibitors of beta amyloid production and derivatives thereof | WYETH | 2004-10-07 | — | — | US | claimed |