Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2612018 | 0.93 | TSHR (0.50) | TSHRTDP1CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL268430 | 0.88 | TSHR (0.73) | TSHRCYP3A4SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL30589890 | 0.88 | TSHR (0.73) | TSHRCYP3A4SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7994441 | 0.86 | TSHR (0.59) | TSHRTDP1CYP3A4SMN1; SMN2LMNA | |
| Ethylene SCHEMBL8565034 | 0.86 | TSHR (0.70) | TSHRCYP3A4SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL15495109 | 0.86 | TSHR (0.59) | TSHRCYP3A4SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5027283 | 0.85 | TSHR (0.68) | TSHRTDP1CYP3A4SMN1; SMN2MAPT | |
| Propene SCHEMBL16859720 | 0.85 | TSHR (0.68) | TSHRCYP3A4SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL2608248 | 0.85 | TSHR (0.57) | TSHRCYP3A4SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL6840513 | 0.85 | TSHR (0.62) | TSHRCYP3A4SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658869-A | Compound with anti-tumor activity and preparation method thereof and the purposes in pharmacy | 复旦大学 | 2018-10-16 | — | — | CN | disclosed |
| US-10030089-B2 | Sugar free, statistical copolymers made from at least three monomers | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-07-24 | — | — | US | disclosed |
| EP-2981563-B1 | SUGAR FREE, STATISTICAL COPOLYMERS MADE FROM AT LEAST THREE MONOMERS | UNIV MINNESOTA (US) | 2018-06-20 | — | — | EP | disclosed |
| US-9944740-B2 | Sugar containing, amphiphilic copolymers | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-04-17 | — | — | US | disclosed |
| EP-2994493-B1 | SUGAR CONTAINING, AMPHIPHILIC COPOLYMERS | UNIV MINNESOTA (US) | 2017-07-19 | — | — | EP | disclosed |
| US-20160120984-A1 | SUGAR CONTAINING, AMPHIPHILIC COPOLYMERS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2016-05-05 | — | — | US | disclosed |
| US-20160120984-A1 | SUGAR CONTAINING, AMPHIPHILIC COPOLYMERS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2016-05-05 | — | — | US | disclosed |
| US-20160083492-A1 | SUGAR FREE, STATISTICAL COPOLYMERS MADE FROM AT LEAST THREE MONOMERS | THE REGENTS OF THE UNIVERSITY OF MINNESOTA | 2016-03-24 | — | — | US | disclosed |
| US-20160083492-A1 | SUGAR FREE, STATISTICAL COPOLYMERS MADE FROM AT LEAST THREE MONOMERS | THE REGENTS OF THE UNIVERSITY OF MINNESOTA | 2016-03-24 | — | — | US | disclosed |
| US-8262931-B2 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, polymer and film | FUJIFILM CORPORATION (JP) | 2012-09-11 | — | — | US | disclosed |
| US-8158021-B2 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, liquid crystalline polymer, and optical anisotropic article | ZEON CORPORATION (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20110233464-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER AND FILM | FUJIFILM CORPORATION (JP) | 2011-09-29 | — | — | US | disclosed |
| US-20110140041-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS, LIQUID CRYSTALLINE POLYMERS AND OPTICALLY ANISOTROPIC MATERIALS | ZEON CORPORATION (JP) | 2011-06-16 | — | — | US | disclosed |
| US-20100258764-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE | ZEON CORPORATION (JP) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160120984-A1 | SUGAR CONTAINING, AMPHIPHILIC COPOLYMERS | SLC2A3, SLC2A1, SLC2A4 | TSHR 4141/4885TDP1 3847/4885CYP3A4 570/4885 |
| US-20160083492-A1 | SUGAR FREE, STATISTICAL COPOLYMERS MADE FROM AT LEAST THREE MONOMERS | SLC2A3, SLC2A4, SLC2A1 | TSHR 4395/4885TDP1 3488/4885CYP3A4 171/4885 |
| US-20110140041-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS, LIQUID CRYSTALLINE POLYMERS AND OPTICALLY ANISOTROPIC MATERIALS | CCNB1, CCNT1, CCNB2 | TSHR 4683/4885TDP1 2657/4885CYP3A4 2338/4885 |
| US-20100258764-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE | LEO1, ZYX, CCNT1 | TSHR 4760/4885TDP1 3187/4885CYP3A4 2218/4885 |
| US-10030089-B2 | Sugar free, statistical copolymers made from at least three monomers | SLC2A3, SLC2A4, SLC2A1 | TSHR 4395/4885TDP1 3488/4885CYP3A4 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.