Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 7/20 | 0.52 |
| ▸ | PDE1A | P54750 | 5/20 | 0.52 |
| ▸ | PDE1C | Q14123 | 5/20 | 0.52 |
| ▸ | USP1 | O94782 | 7/20 | 0.42 |
| ▸ | PDE2A | O00408 | 4/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3010414 | 0.89 | PDE1B (0.65) | PDE1BPDE1APDE1CUSP1PDE2A | |
| SCHEMBL2612342 | 0.88 | PDE1B (0.55) | PDE1BPDE1APDE1CUSP1PDE2A | |
| SCHEMBL3011746 | 0.77 | PDE1B (0.64) | PDE1BPDE1APDE1CPDE2APDE4D | |
| SCHEMBL10201414 | 0.77 | PDE1B (0.65) | PDE1BPDE1APDE1CUSP1PDE2A | |
| SCHEMBL2121444 | 0.77 | PDE1B (0.55) | PDE1BPDE1APDE1CPDE2APDE4D | |
| SCHEMBL2121446 | 0.77 | PDE1B (0.55) | PDE1BPDE1APDE1CPDE2APDE4D | |
| SCHEMBL2612339 | 0.77 | PDE1B (0.55) | PDE1BPDE1APDE1CPDE2APDE4D | |
| SCHEMBL8045647 | 0.76 | PDE1B (0.64) | PDE1BPDE1APDE1CPDE2APDE4D | |
| SCHEMBL2612356 | 0.76 | PDE1B (0.56) | PDE1BPDE1APDE1CPDE2APDE4D | |
| SCHEMBL2454858 | 0.75 | PDE1A (0.48) | PDE1BPDE1APDE1CUSP1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094966-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. | 2012-04-19 | — | — | US | disclosed |
| US-20120094966-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094966-A1 | ORGANIC COMPOUNDS | TPMT, CYP4X1, P2RX4 | PDE1B 4847/4885PDE1A 4868/4885PDE1C 4824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.