⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416289 | 0.71 | — | — | |
| SCHEMBL10160268 | 0.71 | — | — | |
| SCHEMBL13299237 | 0.66 | — | — | |
| SCHEMBL406120 | 0.62 | — | — | |
| SCHEMBL18468237 | 0.59 | — | — | |
| SCHEMBL10531857 | 0.59 | — | — | |
| SCHEMBL8388031 | 0.59 | — | — | |
| SCHEMBL9248291 | 0.59 | — | — | |
| SCHEMBL17551920 | 0.59 | — | — | |
| SCHEMBL12870029 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357159-A1 | QUINOLINE COMPOUNDS AS SELECTIVE AND/OR DUAL MODULATORS OF BILE ACID RECEPTORS AND LEUKOTRIENE CYSTEINYL RECEPTORS | PREC BIO THERAPEUTICS S R L (IT) | 2023-11-09 | — | — | US | disclosed |
| US-11540989-B2 | Hair cosmetic | KAO CORPORATION (JP) | 2023-01-03 | — | — | US | disclosed |
| US-20200368130-A1 | HAIR COSMETIC | KAO CORPORATION (JP) | 2020-11-26 | — | — | US | disclosed |
| US-20180055800-A1 | Pulmonary Delivery for Levodopa | CIVITAS THERAPEUTICS INC (US) | 2018-03-01 | — | — | US | disclosed |
| US-9822064-B2 | Methods of producing cancer treating compounds | INSPYR THERAPEUTICS, INC. (US) | 2017-11-21 | — | — | US | disclosed |
| US-20170018809-A1 | ELECTROLYTE AND ELECTROCHEMICAL DEVICE | DAIKIN INDUSTRIES, LTD. (JP) | 2017-01-19 | — | — | US | disclosed |
| US-20160347706-A1 | Methods of Producing Cancer Compounds | GENSPERA, INC. (US) | 2016-12-01 | — | — | US | disclosed |
| US-9397368-B2 | Non-aqueous electrolyte solution | DAIKIN INDUSTRIES, LTD. (JP) | 2016-07-19 | — | — | US | disclosed |
| US-20160058727-A1 | Pulmonary Delivery for Levodopa | CIVITAS THERAPEUTICS INC (US) | 2016-03-03 | — | — | US | disclosed |
| US-9155699-B2 | Pulmonary delivery for levodopa | CIVITAS THERAPEUTICS, INC. (US) | 2015-10-13 | — | — | US | disclosed |
| US-8404276-B2 | Pulmonary delivery for levodopa | CIVITAS THERAPEUTICS, INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-RE43711-E1 | Pulmonary delivery for levodopa | CIVITAS THERAPEUTICS, INC. (US) | 2012-10-02 | — | — | US | disclosed |
| US-8158793-B2 | Demethylation of 14-hydroxy substituted alkaloid derivatives | SIEGFRIED LTD. (CH) | 2012-04-17 | — | — | US | disclosed |
| US-20110256175-A1 | AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-10-20 | — | — | US | disclosed |
| US-8030336-B2 | Nicotinamide-based kinase inhibitors | YM BIOSCIENCES AUSTRALIA PTY LTD (AU) | 2011-10-04 | — | — | US | disclosed |
| US-20110151008-A1 | Pulmonary Delivery for Levodopa | ALKERMES, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| US-7879358-B2 | Pulmonary delivery for levodopa | ALKERMES, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-7619088-B2 | Demethylation of 14-hydroxy substituted alkaloid derivatives | SIEGFRIED LTD. (CH) | 2009-11-17 | — | — | US | disclosed |
| US-20090163717-A1 | Demethylation of 14-hydroxy substituted alkaloid derivatives | SIEGFRIED AG (CH) | 2009-06-25 | — | — | US | disclosed |
| US-20090137809-A1 | Demethylation of 14 hydroxy substituted alkaloid derivatives | SIEGFRIED LTD (CH) | 2009-05-28 | — | — | US | disclosed |