SCHEMBL2612488

SCHEMBL2612488

COC(=O)CCc1ccc(OP(Oc2ccc(CCC(=O)OC)cc2C(C)(C)C)Oc2ccc(CCC(=O)OC)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.42
PTPN1 P18031 4/20 0.41
SIRT2 Q8IXJ6 1/20 0.39
KMT2A Q03164 3/20 0.39
ALOX5 P09917 1/20 0.39
OR51E2 Q9H255 1/20 0.39
VCAM1 P19320 1/20 0.37
PPARA Q07869 1/20 0.37
MEN1 O00255 2/20 0.36
PTGS1 P23219 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13160827 0.92 GAA (0.39) GAAPTPN1SIRT2KMT2AALOX5
SCHEMBL13893849 0.92 PTPN1 (0.36) GAAPTPN1SIRT2KMT2AALOX5
SCHEMBL13160828 0.90 PTPN1 (0.37) GAAPTPN1SIRT2KMT2AALOX5
SCHEMBL13160807 0.90 GAA (0.40) GAAPTPN1SIRT2KMT2AALOX5
SCHEMBL11983483 0.89 PTPN1 (0.36) GAAPTPN1SIRT2KMT2AALOX5
SCHEMBL2612478 0.86 PTPN1 (0.45) GAAPTPN1SIRT2KMT2AMEN1
SCHEMBL11983497 0.86 PTPN1 (0.38) GAAPTPN1SIRT2KMT2AALOX5
SCHEMBL2612476 0.85 PTPN1 (0.44) GAAPTPN1SIRT2KMT2AALOX5
SCHEMBL2612491 0.85 HRH3 (0.40) GAAPTPN1SIRT2KMT2AALOX5
SCHEMBL9169230 0.84 KMT2A (0.45) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0335262-B1 Phosphite compounds YOSHITOMI PHARMACEUTICAL (JP) 1995-05-31 EP claimed
US-5077424-A Antioxidants YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1991-12-31 US claimed
EP-0335262-A2 Phosphite compounds YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1989-10-04 EP claimed
US-8158039-B2 Method for producing optical film KONICA MINOLTA OPTO INC. (JP) 2012-04-17 US disclosed
US-8158039-B2 Method for producing optical film KONICA MINOLTA OPTO INC. (JP) 2012-04-17 US disclosed
US-8097188-B2 Method of manufacturing optical film KONICA MINOLTA OPTO, INC. (JP) 2012-01-17 US disclosed
US-8097188-B2 Method of manufacturing optical film KONICA MINOLTA OPTO, INC. (JP) 2012-01-17 US disclosed
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
US-7854864-B2 Method for manufacturing an optical film having a convexoconcave structure KONICA MINOLTA OPTO, INC. (JP) 2010-12-21 US disclosed
US-7854864-B2 Method for manufacturing an optical film having a convexoconcave structure KONICA MINOLTA OPTO, INC. (JP) 2010-12-21 US disclosed
US-20070252293-A1 METHOD FOR MANUFACTURING AN OPTICAL FILM HAVING A CONVEXOCONCAVE STRUCTURE, OPTICAL FILM, WIRE GRID POLARIZER AND RETARDATION FILM KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070252293-A1 METHOD FOR MANUFACTURING AN OPTICAL FILM HAVING A CONVEXOCONCAVE STRUCTURE, OPTICAL FILM, WIRE GRID POLARIZER AND RETARDATION FILM KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070227652-A1 FILM FOR DISPLAY, POLARIZING PLATE AND MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-10-04 US disclosed
US-20070227652-A1 FILM FOR DISPLAY, POLARIZING PLATE AND MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-10-04 US disclosed
EP-0335262-B1 Phosphite compounds YOSHITOMI PHARMACEUTICAL (JP) 1995-05-31 EP disclosed
US-5077424-A Antioxidants YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1991-12-31 US disclosed
EP-0335262-A2 Phosphite compounds YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1989-10-04 EP disclosed