Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 8/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 5/20 | 0.37 |
| ▸ | KDR | P35968 | 4/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30613657 | 0.90 | EPHA2 (0.46) | IRAK4SYKEPHA2KDREPHB4 | |
| SCHEMBL26130272 | 0.87 | SYK (0.40) | IRAK4SYKPDK1EPHA2KDR | |
| SCHEMBL26135698 | 0.82 | EPHA2 (0.40) | IRAK4SYKPDK1EPHA2KDR | |
| SCHEMBL31676073 | 0.80 | IRAK4 (0.43) | IRAK4SYKEPHA2 | |
| SCHEMBL26128976 | 0.79 | DRD4 (0.46) | IRAK4PDK1EPHA2KDREPHB4 | |
| SCHEMBL30613693 | 0.77 | EPHA2 (0.46) | IRAK4SYKEPHA2EPHB4 | |
| SCHEMBL26129013 | 0.76 | SYK (0.41) | IRAK4SYKPDK1EPHA2 | |
| SCHEMBL26136052 | 0.74 | IRAK4 (0.41) | IRAK4SYKPDK1EPHA2KDR | |
| SCHEMBL26135462 | 0.74 | IRAK4 (0.41) | IRAK4SYKPDK1EPHA2KDR | |
| SCHEMBL30613661 | 0.73 | EPHA2 (0.48) | IRAK4SYKEPHA2KDREPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023193054-A1 | SPLEEN TYROSINE KINASE INHIBITORS | UNIQUEST PTY LTD (AU) | 2023-10-12 | — | — | WO | disclosed |