⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641482 | 0.85 | — | — | |
| SCHEMBL57470 | 0.78 | — | — | |
| SCHEMBL15063514 | 0.78 | — | — | |
| SCHEMBL27699377 | 0.76 | CA12 (0.35) | — | |
| SCHEMBL28771110 | 0.76 | CA12 (0.35) | — | |
| SCHEMBL2348023 | 0.74 | — | — | |
| SCHEMBL2353732 | 0.74 | — | — | |
| SCHEMBL1401617 | 0.74 | — | — | |
| SCHEMBL4192249 | 0.70 | — | — | |
| SCHEMBL20490013 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016201052-A1 | BRIDGED BICYCLIC KALLIKREIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2016-12-15 | — | — | WO | claimed |
| US-20160362427-A1 | BRIDGED BICYCLIC KALLIKREIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. | 2016-12-15 | — | — | US | claimed |
| US-8133847-B2 | Pyrido[2,3-B]pyrazine derivatives useful as herbicidal compounds | SYNGENTA LIMITED (GB) | 2012-03-13 | — | — | US | claimed |
| US-20090305892-A1 | PYRIDO[2,3-B]PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-12-10 | — | — | US | claimed |
| EP-2057154-A1 | PYRIDO [2, 3-B]PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2009-05-13 | — | — | EP | claimed |
| WO-2008009908-A1 | PYRIDO [2, 3-B] PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2008-01-24 | — | — | WO | claimed |
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |
| EP-2990404-B1 | TETRAZOLINONE COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL CO (JP) | 2020-05-27 | — | — | EP | disclosed |
| EP-3029030-B1 | TETRAZOLINONE COMPOUND, AND USE THEREFOR | SUMITOMO CHEMICAL CO (JP) | 2019-09-04 | — | — | EP | disclosed |
| US-10144746-B2 | Bridged bicyclic kallikrein inhibitors | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2018-12-04 | — | — | US | disclosed |
| US-10077254-B2 | Tetrazolinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-09-18 | — | — | US | disclosed |
| US-20180194780-A1 | BRIDGED BICYCLIC KALLIKREIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. | 2018-07-12 | — | — | US | disclosed |
| EP-3045450-B1 | INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2018-02-07 | — | — | EP | disclosed |
| WO-2004056826-A1 | FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |
| EP-0334120-B1 | ISOXAZOLINES, PROCESS FOR THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1992-05-27 | — | — | EP | disclosed |
| US-4983210-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1991-01-08 | — | — | US | disclosed |
| EP-0144853-B1 | SEMICARBAZIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |
| EP-0334120-A1 | Isoxazolines, process for their preparation and their use | BASF Aktiengesellschaft (DE) | 1989-09-27 | — | — | EP | disclosed |
| US-4725608-A | ANTIINFLAMMATORY, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0144853-A2 | Semicarbazide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |