Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 18/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26130362 | 1.00 | BRD4 (0.48) | BRD4NOTUMMAPK1 | |
| SCHEMBL16721127 | 0.83 | BRD4 (0.48) | BRD4NOTUM | |
| SCHEMBL16721130 | 0.83 | BRD4 (0.48) | BRD4NOTUM | |
| SCHEMBL30574304 | 0.82 | BRD4 (0.47) | BRD4NOTUM | |
| SCHEMBL16721234 | 0.78 | BRD4 (0.58) | BRD4 | |
| SCHEMBL16721157 | 0.78 | BRD4 (0.58) | BRD4 | |
| SCHEMBL16721505 | 0.78 | BRD4 (0.47) | BRD4NOTUM | |
| SCHEMBL16721502 | 0.78 | BRD4 (0.47) | BRD4NOTUM | |
| SCHEMBL16722149 | 0.77 | BRD4 (0.52) | BRD4 | |
| SCHEMBL16721697 | 0.76 | BRD4 (0.78) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196512-A1 | PROPARGYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT MODULATE BRD4 | Plexium, Inc. (US) | 2023-10-12 | — | — | WO | disclosed |