Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16721367 | 0.84 | BRD4 (0.66) | BRD4KDM4EMAPT | |
| SCHEMBL16721365 | 0.84 | BRD4 (0.66) | BRD4KDM4EMAPT | |
| SCHEMBL18871815 | 0.77 | MEN1 (0.46) | — | |
| SCHEMBL16721591 | 0.76 | ROCK1 (0.35) | BRD4KDM4EMAPTROCK1 | |
| SCHEMBL16721589 | 0.76 | ROCK1 (0.35) | BRD4KDM4EMAPTROCK1 | |
| SCHEMBL16721127 | 0.75 | BRD4 (0.48) | BRD4 | |
| SCHEMBL16721130 | 0.75 | BRD4 (0.48) | BRD4 | |
| SCHEMBL13723984 | 0.74 | BRD2 (0.47) | BRD4 | |
| SCHEMBL12502368 | 0.73 | NOTUM (0.43) | ROCK1 | |
| SCHEMBL21531972 | 0.73 | BRD4 (0.62) | BRD4KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196512-A1 | PROPARGYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT MODULATE BRD4 | Plexium, Inc. (US) | 2023-10-12 | — | — | WO | disclosed |