Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.37 |
| ▸ | WNT1 | P04628 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 6/20 | 0.37 |
| ▸ | HTR2C | P28335 | 6/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20096025 | 0.84 | LRRK2 (0.36) | SMN1; SMN2MEN1KMT2ALRRK2 | |
| Hydrochloric Acid SCHEMBL28712275 | 0.78 | GSK3B (0.35) | KDM4EALDH1A1GSK3BDYRK1AWNT1 | |
| SCHEMBL26149351 | 0.78 | CCNK (0.42) | KDM4EALDH1A1POLBGSK3BDYRK1A | |
| SCHEMBL22773938 | 0.75 | HTR2A (0.38) | ALDH1A1GSK3BDYRK1AWNT1MEN1 | |
| Hydrochloric Acid SCHEMBL22773922 | 0.74 | MEN1 (0.37) | ALDH1A1POLBGSK3BDYRK1AWNT1 | |
| SCHEMBL27669059 | 0.74 | KDM4E (0.47) | KDM4EALDH1A1POLBTSHRMAPK1 | |
| SCHEMBL901151 | 0.73 | HTR2A (0.54) | KDM4EPOLBTSHRMAPK1SMN1; SMN2 | |
| SCHEMBL22789383 | 0.72 | KAT2B (0.33) | KDM4EALDH1A1AXLALOX15 | |
| SCHEMBL12082340 | 0.71 | HTR2A (0.55) | ALDH1A1POLBTSHRMAPK1SMN1; SMN2 | |
| SCHEMBL16964100 | 0.71 | POLB (0.40) | KDM4EALDH1A1POLBTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083330-A1 | DRAK2 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 百极优棠(广东)医药科技有限公司 | 2023-05-19 | — | — | WO | disclosed |