Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 1.00 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.76 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | TNF | P01375 | 2/20 | 0.62 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.62 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29228583 | 0.93 | HDAC1 (0.87) | HDAC1HDAC6HDAC4KCNH2KDM4E | |
| SCHEMBL30960755 | 0.93 | HDAC1 (0.87) | HDAC1HDAC6HDAC4KCNH2KDM4E | |
| SCHEMBL12472215 | 0.83 | HDAC6 (1.00) | HDAC1HDAC6HDAC4KCNH2HDAC8 | |
| SCHEMBL25058865 | 0.82 | HDAC6 (1.00) | HDAC1HDAC6HDAC4KCNH2HDAC8 | |
| SCHEMBL20879365 | 0.82 | HDAC1 (0.85) | HDAC1HDAC6HDAC4HDAC8TNF | |
| SCHEMBL26159155 | 0.81 | HDAC1 (0.68) | HDAC1HDAC6KDM4ESMN1; SMN2POLB | |
| SCHEMBL25058864 | 0.81 | HDAC1 (1.00) | HDAC1HDAC6HDAC4KCNH2HDAC8 | |
| SCHEMBL28742702 | 0.80 | HDAC1 (0.81) | HDAC1HDAC6HDAC4KCNH2HDAC8 | |
| SCHEMBL1365734 | 0.79 | HDAC6 (0.70) | HDAC1HDAC6HDAC4KCNH2HDAC8 | |
| SCHEMBL29196444 | 0.79 | HDAC1 (0.84) | HDAC1HDAC6HDAC4KCNH2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159463-A1 | BENZONITRIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI ZHONGZE THERAPEUTICS, CO. LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230159463-A1 | BENZONITRIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI ZHONGZE THERAPEUTICS, CO. LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159463-A1 | BENZONITRIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | HDAC11, HDAC1, HDAC6 | HDAC1 2/4885HDAC6 3/4885HDAC4 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.