Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | JAK1 | P23458 | 3/20 | 0.47 |
| ▸ | JAK3 | P52333 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.40 |
| ▸ | RELA | Q04206 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620380 | 1.00 | SYK (0.52) | SYKNR2F2NPSR1KDM4EMAPT | |
| SCHEMBL29501946 | 1.00 | SYK (0.52) | SYKNR2F2NPSR1KDM4EMAPT | |
| SCHEMBL29501963 | 1.00 | SYK (0.52) | SYKNR2F2NPSR1KDM4EMAPT | |
| SCHEMBL30906009 | 1.00 | SYK (0.52) | SYKNR2F2NPSR1KDM4EMAPT | |
| SCHEMBL23620546 | 1.00 | SYK (0.52) | SYKNR2F2NPSR1KDM4EMAPT | |
| SCHEMBL23925076 | 0.94 | SYK (0.49) | SYKNR2F2NPSR1KDM4EMAPT | |
| SCHEMBL23611090 | 0.92 | JAK3 (0.57) | SYKNR2F2NPSR1KDM4EMAPT | |
| SCHEMBL29502041 | 0.92 | JAK3 (0.57) | SYKNR2F2NPSR1KDM4EMAPT | |
| SCHEMBL29501857 | 0.90 | JAK1 (0.58) | SYKNR2F2NPSR1KDM4EMAPT | |
| SCHEMBL23620439 | 0.90 | JAK1 (0.58) | SYKNR2F2NPSR1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315834-B | Imidazolone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-113121538-B | Furan derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-114315834-A | Imidazolidinone derivatives and their use in medicaments | 成都百裕制药股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-113121573-A | Purine derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-113121538-A | Furan derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2021-07-16 | — | — | CN | disclosed |