Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18706832 | 0.78 | HDAC3 (0.45) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL18707214 | 0.78 | HDAC3 (0.45) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL18707238 | 0.78 | HDAC3 (0.45) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL26326088 | 0.77 | AKT1 (0.50) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL2794680 | 0.77 | HDAC3 (0.51) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL2722481 | 0.76 | HDAC3 (0.53) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL28532859 | 0.76 | HDAC3 (0.53) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL8352132 | 0.76 | AKT1 (0.46) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL22035107 | 0.75 | HDAC1 (0.52) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL3819098 | 0.75 | AKT1 (0.52) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023099592-A1 | ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-06-08 | — | — | WO | disclosed |