Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16905072 | 1.00 | TP53 (0.41) | TP53TSHRSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL15431984 | 0.86 | TP53 (0.48) | TP53TSHRSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL15431973 | 0.80 | — | — | |
| SCHEMBL12385777 | 0.79 | TP53 (0.42) | TP53TSHRSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL4760535 | 0.79 | TP53 (0.42) | TP53TSHRSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL264889 | 0.79 | TP53 (0.42) | TP53TSHRSMN1; SMN2ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL22134139 | 0.77 | TP53 (0.41) | TP53TSHRSMN1; SMN2ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL22134137 | 0.77 | TP53 (0.41) | TP53TSHRSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL3313072 | 0.76 | TP53 (0.44) | TP53TSHRSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL18254449 | 0.74 | TP53 (0.42) | TP53TSHRSMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230190763-A1 | Cyclopentathiophene Carboxamide Derivatives as Platelet Activating Factor Receptor Antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190763-A1 | Cyclopentathiophene Carboxamide Derivatives as Platelet Activating Factor Receptor Antagonists | PTAFR, PDGFRA, PDGFRB | TP53 3918/4885TSHR 205/4885SMN1; SMN2 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.